Lose = Be careful not to lose that.
Loose = The bolts are loose.
There = She is there now.
Their = They have their things.
They're = They're going to the mall.
To = They came to the house.
Too = That's too bad.
Two = 2.
Your = Your dinner is ready.
You're = If you're 150lbs you'd better have a 6 pack.